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Effect of dibutyryl cyclic AMP on morphologic features and biologic markers of a human salivary gland adenocarcinoma cell line in culture

✍ Scribed by Hideo Yoshida; Masayuki Azuma; Tetsuo Yanagawa; Yoshiaki Yura; Yoshio Hayashi; Mitsunobu Sato

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 872 KB
Volume: 57
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19860301)57:5<1011::aid-cncr2820570524>3.0.co;2-x

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## Abstract The prognosis of pancreatic cancer is very poor because of its high malignant potential. To improve the prognosis of pancreatic cancer, a decrease in the grade of maligancy by dibutyryl cyclic AMP (db‐cAMP), a differentiation inducer, was attempted using human pancreatic cancer cell lin