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Effect of dibutyryl cyclic AMP and isoproterenol on 7β-hydroxycholesterol cytotoxicity and esterification in spontaneous transformed cell lines derived from astrocyte primary cultures

✍ Scribed by Patrick Behr; Alexandre Kupferberg; Claude Leray; Laurence Schellenbaum; Paul-Francis Urban; Guy Vincendon; Marcel Mersel


Book ID
115927102
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
350 KB
Volume
313
Category
Article
ISSN
0014-5793

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Differential sensitivity of astrocyte pr
✍ Alexandre Kupferberg; Gérard Cremel; Patrick Behr; Alain Dorsselaer; Bang Luu; M 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 1013 KB

The cytotoxicity of 7 beta-hydroxycholesterol (7 beta-OHC) was investigated on rat astrocyte primary cultures and spontaneously transformed cell lines derived from them. Confluent astrocyte primary cultures (normal cells) were unaffected by 20 microM 7 beta-OHC over a period of 72 h whereas 30 micro