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Effect of diabetogenic nitrosourea on the activity of the pentose phosphate shunt in isolated islets

โœ Scribed by Akpan, Jones O. ;Wright, Peter H. ;Dulin, William E.


Book ID
110565253
Publisher
Springer-Verlag
Year
1982
Weight
751 KB
Volume
19
Category
Article
ISSN
0001-5563

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Diabetogenic action of alloxan-like comp
โœ S. P. C. Tait; M. Poje; B. Rocic; S. J. H. Ashcroft ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 485 KB

Dehydrouramil hydrate hydrochloride (DHU) is an analogue of alloxan which retains the in vivo diabetogenic activity of alloxan but, in contrast to alloxan, is stable in aqueous media at physiological pH. Using rat islets of Langerhans, we have studied the acute effects of DHU on B cell function. Glu