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Effect of dexamethasone on nucleolar casein kinase II activity and phosphorylation of nucleolin in lymphosarcoma P1798 cells

✍ Scribed by Suzuki, Noriaki; Suzuki, Toshikazu; Uchida, Aoi; Thompson, E.Aubrey; Hosoya, Toichiro


Book ID
123040824
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
660 KB
Volume
42
Category
Article
ISSN
0960-0760

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## Abstract Cyclin‐dependent kinase‐5 (CDK5), a unique CDK family member, is active primarily in the central nervous system (CNS). Previous studies suggest that CDK5 is proapoptotic and contributes to tau hyperphosphorylation and neurodegeneration in Alzheimer's disease. The objective of this study