Eighteen surgical patients were studied to determine the effect of anesthesia (general or spinal) and surgery on serum and urinary colony-stimulating factor(s) (CSF). CSF is a leukopoietin that stimulates proliferation of macrophages and granulocytes from bone marrow precursor cells. CSF was assayed
Effect of desloratadine on epithelial cell granulocyte-macrophage colony-stimulating factor secretion and eosinophil survival
β Scribed by J. Mullol; J. Roca-Ferrer; I. Alobid; L. Pujols; A. Valero; A. Xaubet; M. Bernal-Sprekelsen; C. Picado
- Book ID
- 108687636
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 105 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0954-7894
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## Abstract We previously established 2 lung cancer cell lines, OKaβCβ1 and MIβ4, which constitutively produce an abundant dose of granulocyteβcolony stimulating factor (GβCSF) and granulocyte macrophageβcolony stimulating factor (GMβCSF). Many other cases with GβCSF or GMβCSF producing tumors have
GM-CSF is a major regulator of myelopoiesis. Recombinant human GM-CSF (250 micrograms/m2 per day i.v.) was used prior to chemotherapy ("3 + 7" scheme) to recruit leukemic blasts in vivo (de novo AML patients, n = 20) into the chemotherapy sensitive phases of the cell cycle. The stimulatory effect of