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Effect of denervation on the molecular forms of acetylcholinesterase in normal and dystrophic chicken muscles

✍ Scribed by J. Sketelj; M.G. McNamee; B.W. Wilson


Book ID
115896758
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
340 KB
Volume
60
Category
Article
ISSN
0014-4886

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## Abstract Neural regulation of mature normal fast twitch muscle of the chicken suppresses high activity, extrajunctional localization, and isozyme forms of acetylcholinesterase (AChE) characteristic of embryonic, denervated and dystrophic muscle. Normal adult slow tonic muscle of the chicken reta

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Acetylcholinesterase (AChE) molecular forms were studied in normal (NM) and in dystrophic (DM) 129B6F1/ J mouse muscle. Successive extractions of the tissue with saline and saline-Triton X-100 buffers yielded two soluble fractions, S, and S,. Forty percent of the AChE in NM was measured in S, and 60