Effect of Damping Mechanisms on Mass Calibration Equation for MALDI/FTMS

✍ Scribed by Su Yue; Wang Hao-Yang; Guo Yin-Long; Xiang Bing-Ren; An Deng-Kui

• Book ID: 102096115
• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 106 KB
• Volume: 23
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.200591053

✦ Synopsis

Abstract

Collisional damping affects the relationship between ion mass and effective cyclotron frequency in Fourier transform mass spectrometry. The exact mass calibration equation magnified image was therefore derived from the characteristic equation of system model, force $ = m{{{\rm d}v} \over {{\rm d}t}} = qE-qv \times B_{0} - \xi v$ (ξ__v__, a frictional damping force), in which k is amended by the shift of observed frequency of matrix ion or other known ion in external calibration. The mass obtained by the amended calibration equation is therefore immune to collisional damping and space‐charge effects on mass accuracy. The relative errors of ion mass measured were all less than 2×10^‐6^.