Effect of D-400, an Ayurvedic Herbal Formulation on Experimentally Induced Diabetes Mellitus
✍ Scribed by S. K. Mitra; S. Gopumadhavan; T. S. Muralidhar
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 322 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
In the present study, after D-400 treatment a significant reduction in blood sugar levels in alloxan induced diabetes was observed, an oral glucose tolerance test (OGTT) showed a significant lowering of AUC in streptozotocin induced diabetes in rats. There was a rise in hepatic glycogen level closer to normal after D-400 treatment. In the pancreas of diabetic rats, D-400 therapy showed a significant increase in islet number and beta cell count and appeared to bring about blood glucose homeostasis by increasing insulin secretion through repair/ regeneration of endocrine pancreas which may be responsible for the prevention of hepatic glycogenolysis.