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Effect of cyproterone/acetate (SH-714) on plasma prolactin in patients with prostatic cancer

✍ Scribed by Holub, G. ;Lunglmayr, G. ;Spona, J.


Publisher
Springer
Year
1981
Tongue
English
Weight
218 KB
Volume
9
Category
Article
ISSN
0300-5623

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✦ Synopsis


Plasma prolactin was measured in 10 patients with prostatic cancer during treatment with cyproterone acetate (300 mg/week i.m.) Prolactin was assayed during a six month period at weekly intervals during the first 4 weeks and then at monthly intervals. Orchiectomy was not carried out. After 6 months prolactin levels were elevated compared with pre-treatment levels. It is concluded from this study that cyproterone acetate interferes with prolactin secretion by the pituitary gland.


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