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Effect of Cyclosporine and Sirolimus on Fatty Acid Desaturase Activities in Cultured HEPG2 Cells

✍ Scribed by N. Lausada; I.N.T. de Gómez Dumm; J.C. Raimondi; M.J.T. de Alaniz

Book ID
116935261
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
232 KB
Volume
41
Category
Article
ISSN
0041-1345

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Both glucocorticoids and cyclosporine are used to prevent rejection in organ transplant recipients. However, long-term treatment with these drugs is known to induce hyperlipidemia and premature development of atherosclerosis. In previous studies, we have shown that the immunosuppressive drug cyclosp