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Effect of cyclophosphamide on synthesis of antibodies and nonspecific immuno-globulins in mouse spleen cells

โœ Scribed by E. V. Sidorova; L. N. Fontalin; T. K. Novikova; L. A. Pevnitskii

Publisher
Springer US
Year
1977
Tongue
English
Weight
280 KB
Volume
83
Category
Article
ISSN
0007-4888

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Effect of low-dose cyclophosphamide ther
Effect of low-dose cyclophosphamide therapy on specific and nonspecific T cell-dependent immune responses of spleen cells from mice bearing large MOPC-315 plasmacytomas
โœ James A. Wise; Margalit B. Mokyr; Sheldon Dray ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 770 KB

Some T cell-dependent immune parameters were examined in mice bearing a large MOPC-315 plasmacytoma before and after treatment with a low dose (15 mg/kg) of CY. Prior to CY therapy, spleen cells from mice bearing a large MOPC-315 tumor were depressed in their ability to generate an in vitro cytotoxi