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Effect of Cyclin-dependent Kinase (CDK) Inhibition on Expression, Localization and Activity of Maturation Promoting Factor (MPF) and Mitogen Activated Protein Kinase (MAPK) in Bovine Oocytes

✍ Scribed by MD Quetglas; PR Adona; THC De Bem; PRL Pires; CLV Leal

Book ID: 108922303
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 578 KB
Volume: 45
Category: Article
ISSN: 0936-6768
DOI: 10.1111/j.1439-0531.2009.01498.x

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## Abstract Most gastrointestinal stromal tumors (GISTs) have gain‐of‐function mutations of the c‐__kit__ gene. Previously, we found 2 types of gain‐of‐function mutation of the __PDGFRA__ gene, Val^561^ to Asp and Asp^842^ to Val, in about half of GISTs without c‐__kit__ gene mutations. Although th