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Effect of cryopreservation on the activity of CYP450 and glutathione S-transferase in liver slices of dog and monkey

✍ Scribed by Johannes J.M. van de Sandt; Isabel Struik; Winfried R. Leeman; AndréP.M. Wolterbeek; John P. Groten

Book ID
119539224
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
236 KB
Volume
88
Category
Article
ISSN
0378-4274

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The study was designed to investigate the effects of phenobarbital (PB), 3-methylcholanthrene (3-MC), and oltipraz (OPZ), a synthetic derivative of 1,2-dithiole-3-thione, on the levels of cytochrome P450 1A1/2 and gluthathione transferase (GST) mRNAs in both fresh and cryopreserved human, monkey, an