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Effect of copper overload on the survival of HepG2 and A-549 human-derived cells

✍ Scribed by Arnal, N.; de Alaniz, M.; Marra, C.

Book ID
121394769
Publisher
SAGE Publications
Year
2012
Tongue
English
Weight
1023 KB
Volume
32
Category
Article
ISSN
0960-3271

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The uptake of radiocopper by HepGZ cells is a saturable, temperature-dependent and cellular energy-independent process with a V,, of 7.1 f 0.2 pmoles min-' mg protein-' and an estimated K, of 3.3 f 0.5 wM. The rate of copper uptake is reduced at an equimolar concentration of albumin and is unaffecte