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Effect of contraceptive steroids on mammary tumor development in experimental animals

โœ Scribed by El Etreby, M


Book ID
122503200
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
589 KB
Volume
1
Category
Article
ISSN
0165-6147

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This study reports the effect of hematoporphyrin derivative 2 (HPD2) on estrogen receptors (ER) in the animal model used to develop the clinical ER assay. Fifty 200-g female Sprague-Dawley rats were given 20 mg of dimethylbenzanthracene by gastric intubation. Spontaneous mammary tumors occurred in 3