Surface marker expression on peripheral blood mononuclear cells (PBMC) was evaluated daily in PHA- and PWM-stimulated cultures of eight AIDS patients and eight normals. Before culture, the patients' cells showed the characteristic decrease in OKT 4+ cells (normals 40.4%, patients 22.3%; P less than
Effect of conditions of culture and mitogenic stimulation on HLA antigen expression in lymphocytes
β Scribed by A. Yu. Volgin
- Publisher
- Springer US
- Year
- 1981
- Tongue
- English
- Weight
- 268 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0007-4888
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The ability of mouse thymocytes and peripheral blood lymphocytes from rats to synthesize and secrete proteoglycans in the presence of a variety of mitogens and lymphokines was studied in vitro, and it was confirmed that such lymphocytes synthesize and secrete significant quantities of proteoglycans.
## Abstract The effects of antirheumatic drugs on in vitro responses of normal human peripheral blood lymphocytes were examined and found to affect phytomitogen, antigen, and mixed lymphocyte responses. The drugs and concentrations (ΞΌg/ml) at which 50% inhibition (ID50) of phytomitogen stimulation