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Effect of compression temperature on the consolidation mechanism of chlorpropamide polymorphs

โœ Scribed by Makoto Otsuka; Takahiro Matsumoto; Shigesada Higuchi; Kuniko Otsuka; Nobuyoshi Kaneniwa

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
519 KB
Volume
84
Category
Article
ISSN
0022-3549

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The article describes the effect of degree of supersaturation, ฯƒ, on the crystallization of specific polymorphs of phenylbutazone from its methanolic solution at 20ยฐC. At low initial supersaturation, ฯƒ โ‰ค 2.0, the fraction of the metastable ฮฑ polymorph in the crystallized product exceeds that of the