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Effect of cobalt and chromium ions on bcl-2, bax, caspase-3, and caspase-8 expression in human U937 macrophages

✍ Scribed by Alain Petit; Fackson Mwale; David J. Zukor; Isabelle Catelas; John Antoniou; Olga L. Huk

Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
271 KB
Volume
25
Category
Article
ISSN
0142-9612

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## Abstract The main concern associated with metal‐on‐metal (MM) hip prosthesis is the presence of metal ions, mainly chromium (Cr) and cobalt (Co), which are found both systemically and locally in the organism of patients. Previous studies revealed that Cr(III) and Co(II) ions could induce damages