Cisapride (CIS) is a prokinetic agent that increases gastrointestinal motility in normal individuals and improves constipation in Parkinson's disease (PD). We studied the effects of CIS on the clinical response and the peripheral pharmacokinetics of orally administered L-dopa given to patients with
Effect of cisapride on response fluctuations in Parkinson's disease
β Scribed by Dr. Ruth Djaldetti; Maya Koren; Ilan Ziv; Anat Achiron; Eldad Melamed
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 326 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The aim of this study was to assess the outcome of nonmotor fluctuations (NMF) after chronic Subthalamic nucleus (STN) Deep Brain Stimulation (DBS) in Parkinson's disease(PD). Chronic stimulation of the STN has proved to be an effective treatment for advanced PD with motor complications
Loss of dopamine neurons in Parkinson's disease (PD) initiates a complex stream of effects that results in the development of tremor, bradykinesia, and rigidity. While levodopa remains the most effective drug for the symptomatic treatment of PD, its chronic administration is associated with the deve
p < 0.05 by Kruskal-Wallis for difference between the fluctuators and nonfluctuators but not between the untreated and wearing-off groups. 'p < 0.005 by analysis of variance for difference between the fluctuators and nonfluctuators but not between the uncomplicated and wearingoff groups.