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Effect of chronic treatment with recombinant interleukin-2 on the central nervous system of adult and old mice

โœ Scribed by Raffaello Nemni; Sandro Iannaccone; Angelo Quattrini; Salvatore Smirne; Maria Sessa; Monica Lodi; Cristina Erminio; Nicola Canal

Book ID
115803513
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
649 KB
Volume
591
Category
Article
ISSN
0006-8993

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Interleukin 12 (IL-12) exhibits anti-tumor activity in a variety of laboratory models. Although IL-12 itself activates strong anti-tumor activity, the combination of vaccine therapy with IL-2-transduced tumor cells and systemic rIL-12 has been shown to cure tumor-bearing mice more effectively than e