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Effect of chronic administration of p-chlorophenylalanine on sexual receptivity of the female rat

✍ Scribed by David S. Segal; Richard E. Whalen

Publisher
Springer
Year
1970
Tongue
English
Weight
243 KB
Volume
16
Category
Article
ISSN
0033-3158

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✦ Synopsis

It has been postulated that in the female rat sexual receptivity is inhibited by serotonin. This hypothesis was examined by comparing the effects of estrogen and progesterone with the effects of estrogen plus pCPA, a depletor of brain serotonin, on the induction of sexual receptivity. Progesterone was found to facilitate the effects of estrogen on the induction of receptivity, pCPA which induced low levels of brain serotonin did not facilitate estrogen induced receptivity. It was concluded that no direct relationship exists between brain serotonin and receptivity.

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