Effect of cholesterol on calcium-induced aggregation of liposomes and calcium diphosphatidate membrane traversal
β Scribed by Chauhan, Abha; Chauhan, Ved P. S.; Brockerhoff, Hans
- Book ID
- 127012804
- Publisher
- American Chemical Society
- Year
- 1986
- Tongue
- English
- Weight
- 583 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0006-2960
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The present study examined the effect of membrane cholesterol on liposome-mediated calcium phosphate precipitation in metastable aqueous solutions (2.25 mM Ca2+ and 1.5 mM inorganic phosphate) at 22 degrees C, pH 7.4 and 240 mOsm. The liposomes were prepared from 7:2:X molar mixtures of phosphatidyl
The present report compares the effects of different membrane phospholipid (PL)-cholesterol compositions on the kinetics of liposome-mediated formation of calcium phosphates from metastable solutions (2.25 mM CaCl2; 1.5 mM KH2PO4) at 22 degrees C, pH 7.4 and 240 mOsm. In most experiments, the liposo