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Effect of challenge dose and age in experimental infection of pigs with encephalomyocarditis virus

✍ Scribed by C Billinis; L Leontides; V Psychas; V Spyrou; P Kostoulas; F Koenen; O Papadopoulos


Book ID
113942367
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
424 KB
Volume
99
Category
Article
ISSN
0378-1135

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Administration of cyclophosphamide (CY) to guinea pigs infected with a lethal strain of Junin virus (JV) delayed the time of death, with survival of a small number of animals. Virological studies showed a temporary decrease of virus concentration in blood and viscera shortly after the CY injection.