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Effect of celecoxib on proliferation, collagen expression, ERK1/2 and SMAD2/3 phosphorylation in NIH/3T3 fibroblasts

✍ Scribed by Fengfeng Li; Shen Liu; Yuanming Ouyang; Cunyi Fan; Ting Wang; Changqing Zhang; Bingfang Zeng; Yimin Chai; Xiang Wang


Book ID
113589743
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
710 KB
Volume
678
Category
Article
ISSN
0014-2999

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## Abstract Bone tissue homeostasis relies upon the ability of cells to detect and interpret extracellular signals that direct changes in tissue architecture. This study utilized a four‐point bending model to create both fluid shear and strain forces (loading) during the time‐dependent progression