Effect of Cationic Surfactant on the Voltammetric Determination of Chloramphenicol Residue in Milk

✍ Scribed by Chunyan Chai; Minggang Xu; Guoyan Liu

• Publisher: Elsevier Science
• Year: 2006
• Tongue: Chinese
• Weight: 244 KB
• Volume: 34
• Category: Article
• ISSN: 1872-2040
• DOI: 10.1016/s1872-2040(07)60020-6

✦ Synopsis

Effect of cetyltrimethyl ammonium bromide (CTAB), a cationic surfactant, on the voltammetric determination of chloramphenicol at glass-carbon electrode (GCE) was investigated to explore techniques with high sensitivity for detecting the residue of chloramphenicol in biological samples. The results showed that 2 × 10 -5 M CTAB could significantly improve the reductive peak current at the potential of -0.41 V, whereas, the scanning was performed in the range of 0.40 V-0.60 V using 0.02 mol perchloric acid as the supporting solution. Moreover, the linear range of this modified electrochemical method is from 0.0026 mg l -1 to 8 mg l -1 and the detecting limit is 0.83 μg l -1 . Other conditions affecting the determination of chloramphenicol were also discussed in detail.