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Effect of cationic side-chains on intracellular delivery and cytotoxicity of pH sensitive polymer–doxorubicin nanocarriers

✍ Scribed by Fang, Chen; Kievit, Forrest M.; Cho, Yong-Chan; Mok, Hyejung; Press, Oliver W.; Zhang, Miqin

Book ID
120540464
Publisher
The Royal Society of Chemistry
Year
2012
Tongue
English
Weight
795 KB
Volume
4
Category
Article
ISSN
2040-3364

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## Abstract ## Background We have studied the effects of the poly(ethylene glycol) (PEG) chain length and acyl chain composition on the pH‐sensitivity of acid‐labile PEG‐diorthoester (POD) lipids. The optimal conditions are described for preparation of DNA plasmid encapsulated POD nanolipoparticle