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Effect of Carbogen Breathing on the Radiation Response of a Human Glioblastoma Xenograft

โœ Scribed by Janneke Schuuring; Johan Bussink; Hans J. J. A. Bernsen; Wenny Peeters; Albert J. van der Kogel

Book ID
105776419
Publisher
Springer
Year
2006
Tongue
German
Weight
841 KB
Volume
182
Category
Article
ISSN
0179-7158

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Comparison of the effectiveness of tirapazamine and carbogen with nicotinamide in enhancing the response of a human tumor xenograft to fractionated irradiation
โœ Amr El-Said; Douglas Menke; Mary Jo Dorie; J. Martin Brown ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 125 KB ๐Ÿ‘ 2 views

The goal of this study was to compare, with a human tumor xenograft, two different strategies for increasing tumor response to fractionated irradiation, namely, oxygenating the hypoxic tumor cells with carbogen and nicotinamide, or killing these cells with the hypoxic cytotoxin, tirapazamine (TPZ).