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Effect of calcium ions on the scattering of light by heparin

โœ Scribed by S. P. Loucas; K. C. Yeh; H. M. Haddad

Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
242 KB
Volume
60
Category
Article
ISSN
0022-3549

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โœฆ Synopsis

The light-scattering patterns of sodium heparin under the influence of calcium ions were investigated using unpolarized light of 436 nm. A weight average molecular weight on the order of 17,500 was obtained for samples with varying degrees of sulfation. The interaction constant was found to be influenced by the ionic strength of the solution. At fixed electrolyte concentrations, changes in the second virial coefficient were governed by the charge density of the mucopolysaccharide.

Keyphrases

Heparin light scatteringy-effect of calcium+z

Calcium +*-effect on heparin light scattering 0 Molecular weight determination-sulfated heparin strength or degree of sulfation, to exhibit close extrapolation. Mean Mw values on the order of 17,600 and 17,200 with a range of &5%, respectively, were obtained after taking into account a 12% sodium

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