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Effect of calcium channel blockers on theophylline disposition

✍ Scribed by Sirmans, Susan M; Pieper, John A; Lalonde, Richard L; Smith, David G; Self, Timothy H

Book ID
109844318
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
488 KB
Volume
44
Category
Article
ISSN
0009-9236

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Gestational day 11 rat embryos were cultured for 20 h in the presence of nifedipine (NIF), diltiazem (DIL) and verapamil (VER), and the effects of these calcium channel blockers on embryonic heart rate and gross morphology were examined. Reductions of embryonic heart rate were dose dependent and rev