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Effect of C677T methylenetetrahydrofolate reductase polymorphism on plasma homocysteine levels in ethnic groups


Book ID
118631132
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
138 KB
Volume
3
Category
Article
ISSN
1567-5688

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Effect of methylenetetrahydrofolate redu
โœ Giuseppe Toffoli; Antonio Russo; Federico Innocenti; Giuseppe Corona; Salvatore ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 93 KB

## Abstract MTHFR is a critical enzyme that regulates the metabolism of folate and methionine, both of which are important factors in DNA methylation and synthesis. Subjects with the 677Cโ†’T variant have impaired remethylation of Hcy to methionine that could determine hyperhomocysteinemia. Remethyla