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Effect of C-peptide administration on whole body glucose utilization in STZ-induced diabetic rats

✍ Scribed by WU, W. ;OSHIDA, Y. ;YANG, W-P. ;LI, L. ;OHSAWA, I. ;SATO, J. ;IWAO, S. ;JOHANSSON, B-L. ;WAHREN, J. ;SATO, Y.

Book ID: 114424841
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 406 KB
Volume: 157
Category: Article
ISSN: 0001-6772
DOI: 10.1046/j.1365-201x.1996.489236000.x

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## Abstract Insulin‐dependent diabetes mellitus (IDDM) is an autoimmune disease that is characterized by selective destruction of insulin secreting pancreatic islets β‐cells. The formation of cytokines (IL‐1β, IL‐6, TNF‐α, etc.) leads to extensive morphological damage of β‐cells, DNA fragmentation,