Effect of buffer system on the refolding of synthetic ω-conotoxin GVIA

✍ Scribed by James P. Flinn; Roger Murphy

• Book ID: 104634801
• Publisher: Springer Netherlands
• Year: 1996
• Tongue: English
• Weight: 225 KB
• Volume: 3
• Category: Article
• ISSN: 1573-3149
• DOI: 10.1007/bf00132972

✦ Synopsis

We have shown that the yield of native co-conotoxin GVIA after dimethylsulphoxide-mediated oxidative refolding of a synthetic, linear precursor is highly dependant upon the choice of refolding buffer and peptide concentration.