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Effect of Buffer Species on the Inclusion Complexation of Acidic Drug Celecoxib with Cyclodextrin in Solution

โœ Scribed by Mahmoud M. Al Omari; Mohammad B. Zughul; J. Eric D. Davies; Adnan A. Badwan

Book ID
106388699
Publisher
Springer Netherlands
Year
2006
Tongue
English
Weight
287 KB
Volume
55
Category
Article
ISSN
0923-0750

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Complexation of celecoxib with ฮฒ-cyclode
Complexation of celecoxib with ฮฒ-cyclodextrin: Characterization of the interaction in solution and in solid state
โœ V.R. Sinha; R. Anitha; S. Ghosh; A. Nanda; R. Kumria ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 310 KB

Inclusion complexation between celecoxib, a specific cyclooxygenase II inhibitor, and beta-cyclodextrin (b-CD) was studied in solution and solid state. Drug cyclodextrin complexes were prepared by spray drying while physical mixtures were obtained by simple blending. Inclusion complexes were charact