Effect of blocking the pituitary-adrenal system on composition of endogenous colonies of hematopoietic tissue in the spleen of irradiated mice
✍ Scribed by G. N. Sushkevich; É. L. Soboleva; N. A. Zhukova; A. P. Tsygankov
- Publisher
- Springer US
- Year
- 1973
- Tongue
- English
- Weight
- 168 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0007-4888
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A variety of erythropoietic stimuli influenced the number of endogenous spleen colonies in irradiated mice and the number of transplantable colony forming cells in the spleen and marrow of unirradiated mice. Bleeding was the most effective stimulus. Bleeding before irradiation resulted in a 30-fold
## Abstract Hemopoietic colonies were counted macroscopically and microscopically in spleens of hybrid mice seven or eight days after they had been irradiated and given parental bone marrow in donor‐host combinations exhibiting poor growth. Colonies counted microscopically were classified as to dif