𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of autologous mammary tumour extracts on human leukocyte migration in vitro

✍ Scribed by Vagn Andersen; Ole Bjerrum; Gunnar Bendixen; Torben Schiødt; Inger Dissing

Publisher
John Wiley and Sons
Year
1970
Tongue
French
Weight
506 KB
Volume
5
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

In eight out of 22 patients with mammary carcinoma, extract of tumour tissue induced inhibition of autologous leukocyte migration in vitro, demonstrating a state of cellular (delayed type) hypersensitivity. Non‐tumorous tissue did not inhibit migration. The effect of the carcinoma extracts was not due to non‐specific toxicity, since the migration of leukocytes from matched controls was not affected by the extracts.

In nine cases of benign mammary lesions, extracts of autologous mammary tissue did not induce inhibition of migration.

Preliminary results of follow‐up studies in some of the carcinoma patients are reported.

📜 SIMILAR VOLUMES

Effect of salivary gland extract of Leis
Effect of salivary gland extract of Leishmania vector, Lutzomyia longipalpis, on leukocyte migration in OVA-induced immune peritonitis
✍ Marta C. Monteiro; Luciana G. Nogueira; Adelson A. Almeida Souza; José M. C. Rib 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB

Salivary gland extracts (SGE) from Lutzomyia longipalpis potentate L. major infection by inducing a Th2 immune response. However, the effect of SGE on the effector phase of immune response is not known. Herein, we demonstrate that SGE inhibited neutrophil migration in ovalbumin (OVA)-induced periton

Effects of extracts of Tanacetum species
Effects of extracts of Tanacetum species on human polymorphonuclear leucocyte activity in vitro
✍ A. M. G. Brown; C. M. Edwards; M. R. Davey; J. B. Power; K. C. Lowe 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 2 views

The inhibitory effects of whole and fractionated acetone extracts of leaves of four species of Tanacetum were assessed in vitro, using a human polymorphonuclear leucocyte-based bioassay. Biochemical investigation detected the bioactive germacranolide, parthenolide, at high concentrations, in extract