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Effect of ascorbic acid on formaldehyde-mediated DNA oxidation and methylation in human bronchial epithelial cell lines

✍ Scribed by Ke⁎, Y.; Hu, J.; Cheng, J.; Yuan, J.; Xie, X.

Book ID
123206662
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
16 KB
Volume
53
Category
Article
ISSN
0891-5849

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## Abstract Arsenic trioxide (ATO) has been recommended for the treatment of refractory cases of acute promyelocytic leukemia (APL). Recent studies in our laboratory indicated that oxidative stress plays a key role in ATO‐induced cytotoxicity in human leukemia (HL‐60) cells. In the present investig