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Effect of Ascorbic Acid and Its Hydrophobic Derivative Palmitoyl Ascorbate on the Redox State of Primary Human Fibroblasts

✍ Scribed by Rosenblat, Gennady; Graham, Martin F.; Jonas, Adi; Tarshis, Mark; Schubert, Shay Yehoshua; Tabak, Mina; Neeman, Ishak

Book ID
120172427
Publisher
Mary Ann Liebert
Year
2001
Tongue
English
Weight
634 KB
Volume
4
Category
Article
ISSN
1096-620X

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## Abstract Alkaptonuria (AKU) is a rare genetic disease associated with the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products in connective tissues up to the deposition of melanin‐like pigments (ochronosis). Since little is known on the effects of HGA and its metabolite