Effect of Aryl Ring Fluorination on the Antibacterial Properties of C4 Aryl-Substituted N-Methylthio β-Lactams
✍ Scribed by Timothy E Long; Edward Turos; Monika I Konaklieva; Allison L Blum; Amal Amry; Ejae A Baker; Lita S Suwandi; Melodie D McCain; Miti F Rahman; Sonja Dickey; Daniel V Lim
- Book ID
- 108479315
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 300 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0968-0896
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3R)-and (3S)-N-(2-chloromethylphenyl)-3-bromo-3-fluoroazetidin-2-ones 2 were synthesized via the separation of diastereoisomeric phenylglycinol derivatives of the starting 2,3-dibromo-2-fluoropropanoic acid. Acidic hydrolysis of the hydroxyamides led to the chiral trihalogenopropanoic acids. Then, a
## Abstract New pyrrolo[3,4‐c]pyrrole‐1,4‐dione (DPP) derivatives carrying 3,4‐ethylenedioxy‐thiophenylphenyl (EDOT‐phenyl) substituent groups in the 3‐ and 6‐position, or in the 2‐ and 5‐position of the DPP chromophore were synthesised and electrochemically polymerised. The properties of the polym