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Effect of Application Volume and Area on the Absorption of Phenol Red, as a Model Drug, from the Liver Surface in Rats

✍ Scribed by KOYO NISHIDA; NORIHITO SATO; YUKI NAKAKOGA; TAKAHIRO MUKAI; HITOSHI SASAKI; JUNZO NAKAMURA


Book ID
118110468
Publisher
Pharmaceutical Press
Year
1997
Tongue
English
Weight
485 KB
Volume
49
Category
Article
ISSN
2042-7158

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The effect of oral dose volume on the ab
✍ David F. Nickerson; Margaret L. Weaver; Francis L. S. Tse πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 488 KB πŸ‘ 3 views

## Abstract The influence of dose volume on drug absorption following oral administration of a highly and a poorly water soluble drug was examined in male Sprague‐Dawley rats. A constant mass of each ^14^C‐labeled compound was given via gavage in dose volumes of 1, 5, 10, and 20 mL kg^βˆ’1^. Blood le