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Effect of antiinflammatory drugs on human interleukin-1-induced cartilage degradation

✍ Scribed by E. C. Arner; L. R. Darnell; M. A. Pratta; R. C. Newton; N. R. Ackerman; W. Galbraith


Publisher
SP Birkhäuser Verlag Basel
Year
1987
Tongue
English
Weight
244 KB
Volume
21
Category
Article
ISSN
1420-908X

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✍ John R. Hubbard; Dr. James J. Steinberg; Michael S. Bednar; Clement B. Sledge 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 744 KB

The effects of highly purified human monocyte-derived interleukin-1 (IL-1) on bovine nasal cartilage breakdown were investigated. Cartilage degradation was determined by quantifying the fraction of total proteoglycan released from cartilage during 8 days of culture. The response appeared to be chond