Effect of antihypertensive drugs on plasma benin activity and urinary excretion of prostaglandin E2
β Scribed by M. Blum; A. Algueti; S. Bauminger; A. Aviram; D. Ayalon
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 305 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0161-4630
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π SIMILAR VOLUMES
Cyclooxygenase (COX) converts arachidonic acid to prostaglandin (PG) H 2 , which is further metabolized to various prostaglandins, prostacyclin and thromboxane A 2 . COX exists in at least two different isoforms. COX-1 is constitutively expressed, whereas COX-2 is induced by proinflammatory stimuli.
## Abstract Increasing experimental, clinical, and epidemiological studies point to the pivotal role of inflammation in the pathogenesis of acute and chronic neurodegenerative diseases and to the protective effects of nonsteroidal antiinflammatory drug (NSAID) therapies. Nonetheless, NSAID longβter