Effect of anH-2mutation on cytotoxic T cell recognition. Specific antigen can determine the pattern ofH-2restriction

Mutations inH-2Kbinfluence the specifici

Mutations inH-2Kbinfluence the specificity of alloreactive effector cells included in the repertoire ofH-2Db-restricted cytotoxic T lymphocytes against Moloney leukemia virus

✍ Marijke J. Stukart; Jolande Boes; Cornelis J. M. Melief 📂 Article 📅 1983 🏛 Springer-Verlag 🌐 English ⚖ 579 KB

Moloney leukemia virus-specific cytotoxic T lymphocytes (CTL), generated by secondary in vitro stimulation of spleen cells with syngeneic virusinfected cells, frequently lysed not only syngeneic virus-infected cells, but also noninfected allogeneic target cells. This phenomenon was studied with B6(H