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Effect of analogs with modified prenyl side chains on growth of serum deficient HL60 cells

✍ Scribed by I. L. Sun; L. E. Sun; E. E. Sun; F. L. Crane; R. Willis


Book ID
112010554
Publisher
IOS Press
Year
2003
Tongue
English
Weight
67 KB
Volume
18
Category
Article
ISSN
0951-6433

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Numerous vitamin D3 analogs (VDAs) can inhibit the proliferation of cells from several types of human malignancies. The physiologically active form of vitamin D3, 1,25-dihydroxyvitamin D3(l ,25D3), is formed by successive hydroxylations of cholecalciferol at the 25 and la positions. In this study we