Characterization of a tumorigenic murine
โ
Varda Mann; Moshe Szyf; Aharon Razin; Evelyne Chriqui-Zeira; Eli Kedar
๐
Article
๐
1986
๐
John Wiley and Sons
๐
French
โ 593 KB
The establishment of IL-2-independent T-cell lines spontaneously derived from long-term IL-2-dependent cytotoxic T-cell lines is described. Two lines (cloned and uncloned) studied in detail have shown the following characteristics: (1) Permanent loss of IL-2 dependence. (2) Partial or complete loss