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Effect of an immunosuppressive factor-derived from choriocarcinoma cell lines on IL-2 dependent T cell response

โœ Scribed by T. Kameda; N. Matsuzaki; K. Sawai; T. Okada; F. Saji; O. Tanizawa


Book ID
119090958
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
62 KB
Volume
15
Category
Article
ISSN
0165-0378

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The establishment of IL-2-independent T-cell lines spontaneously derived from long-term IL-2-dependent cytotoxic T-cell lines is described. Two lines (cloned and uncloned) studied in detail have shown the following characteristics: (1) Permanent loss of IL-2 dependence. (2) Partial or complete loss