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Effect of amyloid β on capacitive calcium entry in neural 2a cells

✍ Scribed by Ying Niu; Zuqi Su; Chang Zhao; Bo Song; Xiufang Zhang; Nanming Zhao; Xun Shen; Yandao Gong

Book ID: 116326863
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 557 KB
Volume: 78
Category: Article
ISSN: 0361-9230
DOI: 10.1016/j.brainresbull.2008.10.003

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Beta-amyloid1-42 (Abeta) is a naturally occuring peptide whose accumulation in the brain is putatively coupled to Alzheimer's disease pathogenesis. Deleterious effects of Abeta on neurons have been linked to the inappropriate activation of signaling pathways within the cell (reviewed in Yankner, 199