Effect of amyloid beta peptides Aβ1–28and Aβ25–40on model lipid membranes
✍ Scribed by Maksim Ionov; Barbara Klajnert; Konstantinos Gardikis; Sophia Hatziantoniou; Bartlomiej Palecz; Bakhtiyar Salakhutdinov; Josep Cladera; Maria Zamaraeva; Costas Demetzos; Maria Bryszewska
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 275 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0022-5215
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline due to neuronal loss and neural network dysfunction. It has been postulated that progressive neuronal loss in AD is consequence of the neurotoxic properties of the amyloid‐β peptide (Aβ). In the p
Elevated levels of zinc 2+ and copper 2+ are found chelated to the amyloid-beta-peptide (Ah) in isolated senile plaque cores of Alzheimer's disease (AD) patients. However, the precise residues involved in Zn 2+ ligation are yet to be established. We have used 1 H NMR and CD to probe the binding of Z