Effect of aminoglycoside antibiotics on the autolytic enzyme ofStreptomyces griseus

✍ Scribed by István Szabó; András Penyige; György Barabás; Judit Barabás

• Publisher: Springer
• Year: 1990
• Tongue: English
• Weight: 336 KB
• Volume: 155
• Category: Article
• ISSN: 0302-8933
• DOI: 10.1007/bf00291282

✦ Synopsis

The isolated cell wall of Streptomyces griseus 52-1 strain labelled with fluorescein isothiocyanate (FITC) and containing wall-bound autolytic enzyme was lysed as a function of different cations. The autolysis was accelerated by aminoglycoside antibiotics (streptomycin and the structurally closely related neomycin) which have a polycationic character. Since this strain is a streptomycin producer it is suggested that streptomycin may have a regulatory function on autolysis.