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Effect of Altered Blood Plasma Osmolalities on Regional Brain Amino Acid Concentrations and Focal Seizure Susceptibility in the Rat

✍ Scribed by Claude F. Baxter; Claude G. Wasterlain; Kristine L. Hallden; Sharon F. Pruess

Book ID
111173884
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
814 KB
Volume
47
Category
Article
ISSN
0022-3042

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✍ Gregory L. Holmes; James L. Thompson; G. Franklin Carl; Brian S. Gallagher; Jeff πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 English βš– 488 KB

There is now considerable evidence that the N-methyl-D-aspartic acid receptor is important in the genesis of seizures. One of the selective antagonist of the NMDA receptor is 2-amino-7-phosphonoheptanoic acid (APH). In this study we evaluated the effects of intracerebroventricular (i.c.v.) administr