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Effect of alterations in the cyclopentane ring on bone resorptive activity of prostaglandin

โœ Scribed by L.G. Raisz; F.N. Woodiel

Book ID
119051006
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
318 KB
Volume
37
Category
Article
ISSN
0090-6980

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โœ Alessandra R Rufino; Francisco C Biaggio ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 109 KB

A novel prostaglandin analogue, n-heptyl-4-(3-hydroxy-trans-1-octenyl)-1,3-thiazolidin-2-thione, containing heteroatoms in the ring has been synthesized. The key step in the synthesis was the preparation of the five-membered ring starting from of L-cysteine ethyl ester hydrochloride.