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Effect of allopurinol on oxidant stress and hepatic function following ischemia and reperfusion in the rat

✍ Scribed by Jacques Metzger; Bernhard H. Lauterburg


Book ID
114796616
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
457 KB
Volume
8
Category
Article
ISSN
0106-9543

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This study was done to determine the relationship between microsomal lipid peroxidation during hepatic ischemia/reperfusion and alteration in cytochrome P-450-dependent drug metabolism. Rats were pretreated with a-tocopherol to inhibit lipid peroxidation or with vehicle (soybean oil) and then subjec